AI in 2026: Reid Hoffman’s Predictions on Agents, Work, and Creation

From cofounding LinkedIn to backing OpenAI early,Reid Hoffman is in the habit of being right about the future, so we wanted to know what he saw coming in 2026. In histhirdappearance onAI & I, Hoffman lays out his predictions for where AI will go in the 12 months ahead. He talks toDan Shipper about how agents will break out of coding into other domains and who’s winning the coding agent race. They also get into how Hoffman definesartificial general intelligence, the way he believes enterprises will use AI, and why public debate on AI might turn more negative, even as the technology becomes more empowering for individuals. Hoffman’s other bets on the future include cofounding AI drug discovery startupManas AI, investing at venture capital firmGreylock Partners, writingbooks, and hosting theMasters of Scale podcast. He’s alsoan investor at Every. If you found this episode interesting, please like, subscribe, comment, and share! ** Want even more? ** Sign up for Every to unlock our ultimate guide to prompting ChatGPT here:https://every.ck.page/ultimate-guide-to-prompting-chatgpt. It’s usually only for paying subscribers, but you can get it here for free. To hear more from Dan Shipper: - Subscribe to Every:https://every.to/subscribe - Follow him on X:https://twitter.com/danshipper Timestamps: 00:00:00 - Start 00:00:52 - Introduction 00:02:20 - The future of work is an entrepreneurial mindset 00:05:22 - Creation is addictive (and that’s okay) 00:09:22 - Why discourse around AI might get uglier this year 00:17:03 - AI agents will break out of coding in 2026 00:24:18 - What makes Anthropic’s Opus 4.5 such a good model 00:28:46 - Who will win the agentic coding race 00:36:13 - Why enterprise AI will finally land this year 00:43:16 - How Hoffman defines AGI 00:55:33 - The most underrated category to watch in AI right now ** Links to resources mentioned in the episode: ** - Reid Hoffman:Reid Hoffman (@reidhoffman) - The AI drug discovery startup Hoffman cofounded:Manas AI